Endocrine Abstracts

Introduction: Due to the absence of randomized controlled trials, management of low risk papillary thyroid cancer (PTC), which represents the most commonly diagnosed form of thyroid malignancy, remains controversial. Hashimoto’s thyroiditis (HT) is significantly more frequent in patients with PTC, as compared with subjects carrying benign lesions as well as different tumour histotypes. Despite still controversial, HT is considered a protective factor in PTC being associat...

Objectives: Molecular techniques are becoming increasingly important for the management of thyroid nodules. In particular, next-generation sequencing (NGS) can assess multiple predictive biomarkers simultaneously, enabling more accurate pre-operative risk stratification for patients with indeterminate fine-needle aspirates and identifying specific molecular alterations for targeted therapy in patients affected by advanced, radioactive iodine refractory carcinomas. To meet thes...